Remedy · chemical
Capsaicin (topical)
Also: cayenne extract, capsicum
A chili-pepper extract rubbed on the skin to dull localized pain.
Active compounds Capsaicin
Evidence by condition
Each grade reflects the research for Capsaicin (topical) and that condition specifically.
- BKnee osteoarthritis
Applied to the skin, reduces OA joint pain vs placebo — at the cost of frequent transient burning at the site.
1 citation
- Efficacy and safety of topical capsaicin in the treatment of osteoarthritis pain: A systematic review and meta-analysis Meta-analysis 2024 · n=498 · Phytotherapy Research · PMID 38761115 · DOI 10.1002/ptr.8223
- Efficacy and safety of topical capsaicin in the treatment of osteoarthritis pain: A systematic review and meta-analysis
- BChronic musculoskeletal pain
Useful for localized musculoskeletal pain when rubbed on the affected area.
1 citation
- Efficacy and safety of topical capsaicin in the treatment of osteoarthritis pain: A systematic review and meta-analysis Meta-analysis 2024 · n=498 · Phytotherapy Research · PMID 38761115 · DOI 10.1002/ptr.8223
- Efficacy and safety of topical capsaicin in the treatment of osteoarthritis pain: A systematic review and meta-analysis
Wash hands thoroughly after applying, and expect burning for the first several uses — it usually fades with regular use.