Active compound
Capsaicin
capsaicinoid (alkaloid)
The pungent compound in chili peppers, used topically for pain.
Mechanism
A TRPV1 agonist: initial excitation of pain-sensing C-fibers followed by reversible "defunctionalization" of the nerve terminals.
TRPV1 substance P
Found in
Remedies that contain Capsaicin.
- Capsaicin (topical) chemical B Moderate