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Active compound

Curcuminoids

polyphenol (curcuminoid)

The yellow pigments of turmeric, chiefly curcumin, studied for anti-inflammatory effects.

Mechanism

Inhibit NF-κB and downstream inflammatory cytokines (TNF-α, IL-1β) and the COX-2 / 5-LOX pathways.

NF-κB COX-2 5-LOX TNF-α IL-1β

Found in

Remedies that contain Curcuminoids.

Curcumin is poorly absorbed on its own, so studied products usually pair it with piperine or use a bioavailability-enhanced formulation.